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The liver function test was carried out by Adicon Clinical Laboratories (Shanghai, China) with Automatic Chemistry Analyzer 640 (OLYMPUS, Japan). Histopathology examination The livers of 5 mice from the same two treated groups, untreated control group and uninfected group corresponding to liver function tests were rapidly excised, washed twice with normal saline and fixed in 10 neutral buffered formal. For statistical purposes, the severity of histopathological changes was measured on a semi-quantitative scale scored in four categories according to the intensity of alterations: without alteration (0), slightly altered (1), intermediately altered (2) and strongly altered (3).